5-Amino-1MQ 50 mg

Description

5-Amino-1MQ (5-Amino-1-Methylquinolinium) is a synthetic small-molecule compound extensively studied for its ability to inhibit Nicotinamide N-Methyltransferase (NNMT), an enzyme involved in cellular methylation pathways and metabolic regulation.

Due to its mechanism of action, 5-Amino-1MQ has become an important research compound in studies investigating energy metabolism, adipose tissue biology, cellular bioenergetics, and metabolic homeostasis.

Research Applications

• Nicotinamide N-Methyltransferase (NNMT) research
• Cellular metabolism investigations
• Energy homeostasis studies
• Adipose tissue biology
• Methylation pathway research
• Metabolic signaling investigations
• Experimental pharmacology
• Molecular and cellular biology

This product is supplied as lyophilized powder for research purposes only.

Scientific Background

5-Amino-1MQ is a synthetic quinolinium derivative developed as a selective inhibitor of Nicotinamide N-Methyltransferase (NNMT), an intracellular enzyme responsible for catalyzing the methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor.

NNMT has been widely investigated for its role in regulating cellular metabolism, methyl donor availability, NAD⁺ metabolism, and energy homeostasis. Experimental studies have explored the effects of NNMT inhibition on adipocyte biology, mitochondrial function, glucose metabolism, and cellular bioenergetics.

Because of its selectivity and well-characterized pharmacological profile, 5-Amino-1MQ has become a valuable research compound for investigating metabolic regulation, enzyme inhibition, and intracellular signaling pathways.

Key Features

• Synthetic NNMT inhibitor
• Selective inhibitor of Nicotinamide N-Methyltransferase
• Extensively studied in metabolic research
• Research focus on cellular energy metabolism
• Lyophilized powder
• ≥99% purity
• Manufactured for laboratory research only

Specifications

• Product Name: 5-Amino-1MQ
• Content: 50 mg
• Format: Lyophilized Powder
• Purity: ≥99%
• Storage: Store refrigerated at 2–8°C. Protect from light and moisture.
• Reconstitution: Reconstitute using bacteriostatic water or sterile water intended for laboratory research.
• Research Grade: Laboratory Research Material

Disclaimer

For Research Use Only (RUO). This product is intended exclusively for laboratory and scientific research. It is not intended for human consumption, veterinary use, diagnosis, treatment, or prevention of any disease.